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Victoria Epilepsy & Parkinson's Centre

Epilepsy Blog

Clobazam (Frisium) Shortage Update - May 12, 2016

Over the past few days we have had reports that pharmacies are having difficulty getting clobazam from their suppliers. This suggests that the clobazam shortage is worsening. The best source of information about the supply of your medication is your pharmacist.

The situation will vary from one drug store to another, depending on the amount their supplier has available, whether the pharmacy keeps stock of this drug on-hand or orders it as needed, and other factors.

There are 3 manufacturers of clobazam:

  • Apotex Inc. (Apo-Clobazam)
  • Teva Canada Ltd. (Teva-Clobazam or Novo-Clobazam)
  • Lundbeck (Frisium)

See below for estimated resupply dates.

Pharmascience discontinued PMS-Clobazam in April 2015.

What should I do if I take clobazam (Frisium)?

If you or one of your family members take clobazam, we advise that you contact your drug store and ask about the supply of this medication.If your pharmacy is unable to refill your prescription, another pharmacy may be able to.

  • Contact your healthcare provider for medical advice if you are unable to get your prescription refilled.
  • Clobazam is a benzodiazepine and should not be stopped abruptly.
  • If clobazam is unavailable, your healthcare provider may prescribe an alternate drug to prevent benzodiazepine withdrawal and to control your seizures.
  • Work closely with your healthcare provider and your pharmacist throughout the shortage.

If you need information or assistance regarding a drug shortage, please contact your local epilepsy agency by calling 1-866-EPILEPSY (1-866-374-5377).

Estimated Resupply Dates:

Apotex Inc. posted a shortage of Apo-Clobazam in early December on No explanation has been provided. The estimated resupply date for Apo-Clobazam has changed multiple times, initially it was April 15, 2016 then it was extended to September 1, 2016. The newest resupply estimate is November 30, 2016.

Teva-Clobazam (also called Novo-Clobazam) from Teva Canada Ltd. is also on back-order and new shipments are not expected to be available until September 30, 2016.

Frisium is on allocation, so pharmacies can only order limited quantities.

There have been no reports, so far, on from Teva Canada Ltd. or Lundbeck.

Posted by Suzanne Nurse,Chair, Canadian Epilepsy Alliance Dr on 25th May 2016 11:54am